The second highest mountain in the Zillertal Alps - after Mt. Gran Pilastro - is the 3,480 m high Gran Mèsule.
Mt. Gran Mèsule (Grosser Möseler in German) is located in the Zillertal Main Crest at the border between South and North Tyrol. As second highest peak of the Zillertal Alps, it is surrounded by further three-thousanders, like the Möselekopf (3,390 m a.s.l.), the secondary peak of Mt. Gran Mèsule which is separated from the main peak by the Forcella del Mèsule wind gap, Mt. Dosso Largo (3,215 m a.s.l.), Mt. Furtschaglspitze (3,188 m a.s.l.) and Mt. Cima di Campo (3,418 m a.s.l.).
In June 1865, G. H. Fox, Douglas William Freshfield and Francis Fox Tuckett with their mountain guides François Devouassoud from Chamonix and Peter Michel from Grindelwald climbed the mountain for the first time. The summit (3,480 m a.s.l.) is accessible nowadays from the Furtschaglhaus hut in North Tyrol, a demanding glacial and rock tour of about 4 hours.
But the top can also be reached from the south in the same time via the Neves High Route, starting at the Rif. Giovanni Porro mountain hut above Lake Neves in South Tyrol (2,419 m a.s.l.). Other starting points are the Rif. Passo Ponte mountain hut at the Ponte di Ghiaccio mountain pass (and then along the above mentioned Neves High Route) and the Berliner Hütte mountain hut in the Zillertal valley (2,042 m a.s.l.), one of the largest mountain huts in the Zillertal Alps.